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Abstract #3523

Cross-Sectional Analysis of the Correlation between Non-Alcoholic Fatty Liver Disease and Whole-Body Fat Distribution Characteristics

Jianxian Liu1, Jie Gan1, Xin Wang1, Zhengyi li1, Zhensong Wang1, Chuanli Cheng2, Chao Zou2, and Dan Yu3
1Shandong University Affiliated Shandong Provincial Third Hospital, Jinan, China, 2Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, 3United Imaging Research Institute of Intelligent Imaging, Beijing, China

Synopsis

Keywords: Fat & Fat/Water Separation, Fat and Fat/Water Separation, Nonalcoholic fatty liver disease (NAFLD)

Motivation: Nonalcoholic fatty liver disease (NAFLD) is an escalating health issue, urgently requiring a comprehensive analysis of abnormal fat deposition and distribution in the body.

Goal(s): To explore the correlation between NAFLD and whole-body fat distribution, visceral fat infiltration, and musculoskeletal fat deposition.

Approach: Utilize high-precision whole-body fat quantification to analyze fat distribution and proton density fat fraction (PDFF) in various tissues, with a focus on clinical applicability for NAFLD.

Results: High-precision whole-body fat quantification demonstrated good correlations in NAFLD, proving its capability to identify systemic lipid metabolic disorders in clinical diagnostics.

Impact: High-precision whole-body fat quantification offers a non-invasive, accurate method for assessing fat distribution, potentially revolutionizing NAFLD diagnosis and classification, setting new clinical standards, and guiding future advancements in lipid metabolic disease diagnostics.

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Keywords