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Abstract #3524

Generation of Water Selective Radiofrequency Pulses for Fat Suppression Using Optimal Control

Marek Obajtek1, Alexander Jaffray1, Andrew Yung2, Alexander Rauscher1,2,3, and Christina Graf1,3
1Department of Physics & Astronomy, University of British Columbia, Vancouver, BC, Canada, 2Department of Radiology, University of British Columbia, Vancouver, BC, Canada, 3Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada

Synopsis

Keywords: Fat & Fat/Water Separation, Fat and Fat/Water Separation

Motivation: To develop B1-robust excitation pulses that can remove fat signal from images using optimal control.

Goal(s): To establish an optimal control framework for B1-robust design of water-selective excitation pulses. The pulse is optimized to excite the water signal without affecting the fat signal.

Approach: The water-selective properties of the optimal control excitation pulse are tested in a water-mineral oil phantom with controlled B1-inhomogeneities to assess performance.

Results: The optimized pulse achieves precise excitation of water within the phantom and maintains this selectivity under inhomogeneous B1-conditions. Fat magnetization is effectively unchanged by the pulse, even in the presence of B1-variations.

Impact: This work demonstrates the feasibility of designing B1-robust, water-selective excitation pulses using optimal control that leave the fat signal unexcited. Initial tests in a fat-water phantom align with simulations.

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Keywords