Keywords: Prenatal, Placenta
Motivation: Whether arterial spin labeling (ASL) can be used to assess placental dysfunction in pregnant women with gestational diabetes mellitus (GDM) or fetal growth restriction (FGR) remains to be explored.
Goal(s): To explore the changes in placental blood flow in pregnant women with GDM or FGR compared with normal pregnancies.
Approach: Placental blood flow (PBF) values of 13 normal pregnancy women, 4 women with FGR, and 2 with GDM were obtained using pseudocontinuous ASL (pCASL) and compared using unpaired t-test.
Results: Both FGR and GDM pregnancies showed lower PBF compared to normal pregnant subjects.
Impact: PCASL is a useful non-invasive tool for measuring placental blood flow in pregnant women, which may aid in diagnosing pathological developments or abnormalities in the placenta of pregnancies.
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