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Abstract #3635

Development of a ventricular cerebrospinal fluid dynamics phantom

Tatsuya Oki1, Makoto Yoshigoe1, Shinnosuke Hiratsuka1, Shota Ishida2, Masahiro Yoshimura1, and Yoshiyuki Watanabe1
1Department of Radiology, Shiga University of Medical Science, Otsu, Japan, 2Department of Radiological Technology, Kyoto College of Medical Science, Nantan, Japan

Synopsis

Keywords: Phantoms, Phantoms, cerebrospinal fluid dynamics, 4D-flow MRI

Motivation: Although phantom studies are required to establish a method for measuring the ventricular cerebrospinal fluid (CSF) flow, there is no phantom that can simulate its dynamics.

Goal(s): To develop a ventricular CSF dynamics phantom.

Approach: We generated complex flow within the simulated ventricles by pulsatile flow from a pump to expand and contract the simulated lateral ventricle wall, and validated whether designed flow occurred using 4D-flow MRI.

Results: We could generate CSF pulsation within the simulated ventricles and set both the stroke volume and average flow velocity in the simulated ventricles flexibly by adjusting the stroke volume of a pump.

Impact: A phantom capable of simulating the complex cerebrospinal fluid (CSF) flow within the ventricles promotes fundamental research toward establishing optimal measurement methods of CSF flow, which is currently a challenge in the analysis of CSF dynamics.

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Keywords