Keywords: Aging, Nerves, Quantum sensing
Motivation: Functional MRI techniques such as DIANA have been controversial in direct detection of neuronal electrical activities (firings) due to tiny difference between task vs. resting state. Quantum-sensing (qs) MRI is an emerging non-BOLD fMRI technique that has the potential for the direct detection.
Goal(s): To explore whether qsMRI detects neuronal firings during a task of finger-tapping.
Approach: A group of healthy subjects (age 27–84 years) was studied on a 3T MRI scanner.
Results: The qsMRI was able to detect firings, with older people showing higher firing rate during tapping than resting.
Impact: This positive outcome will encourage researchers to use the qsMRI in a wide range of studies on brain functions and neurological disorders including normal aging and Alzheimer’s disease.
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