Keywords: Microstructure, Cancer
Motivation: Breast cancer is a leading cause of cancer-related deaths and is highly heterogeneous, requiring precise subtype classification for personalized treatment.
Goal(s): To assess the capability of multi-dimensional diffusion MRI (MD-dMRI) in differentiating between benign and malignant breast lesions and identifying molecular subtypes of breast cancer.
Approach: A prospective study involving 76 patients with suspected breast lesions was conducted. MD-dMRI scans were performed, and quantitative parameters reflecting tissue heterogeneity were analyzed.
Results: MD-dMRI parameters showed significant differentiation between benign and malignant lesions. The CMD and MKI parameters provided valuable insights into molecular subtypes, supporting personalized therapeutic strategies.
Impact: MD-dMRI enhances breast cancer diagnosis and subtype identification, improving precision medicine. It offers non-invasive, accurate insights into tumor heterogeneity, guiding personalized treatment and potentially improving patient outcomes and survival rates.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords