Keywords: Microstructure, Cancer, Ovarian Cancer
Motivation: Preoperative differentiation between benign ovarian lesions and epithelial ovarian cancers (EOCs), and further subclassification type I and II EOCs, is essential for guiding treatment.
Goal(s): To evaluate MRI cytometry-derived microstructural parameters for noninvasive differentiating benign ovarian lesions and EOCs, and between type I and II EOCs.
Approach: MRI cytometry extracted microstructural parameters, including diameter, intracellular volume fraction, cellularity and extracellular diffusivity. Diagnostic abilities were evaluated using unpaired two-tailed t-tests, linear regression, AUC, sensitivity and specificity.
Results: Microstructural parameters showed significant differences and strong diagnostic performance for distinguishing benign ovarian lesions from EOCs and differentiating type I and II EOCs.
Impact: For the first time, MRI cytometry demonstrated high feasibility and diagnostic accuracy for non-invasively distinguishing benign ovarian lesions from epithelial ovarian cancers (EOCs) and further differentiating between type I and II EOCs.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords