Keywords: Microstructure, Diffusion Analysis and Visualization, Soft tissue tumors
Motivation: Ki-67 expression is a key indicator of malignant tumor proliferation and is closely linked to the prognosis of soft tissue tumors.
Goal(s): This study aimed to assess the correlation between each quantitative parameter of IMPULSED based on time-dependent diffusion MRI (td-dMRI) data parameters and Ki-67 expression.
Approach: Spearman correlation analysis was performed to evaluate the relationship between parameters derived from td-dMRI and Ki-67 levels.
Results: Significant correlations were found between parameters derived from td-dMRI (cellularity, vin, Dex, ADC0Hz, ADC25Hz, ADC40Hz, cADC, and rcADC) and Ki-67, suggesting the potential of td-dMRI as a noninvasive tool for assessing tumor proliferation.
Impact: Time-dependent diffusion MRI provides a noninvasive method for preoperative evaluation of malignant proliferation in soft tissue tumors, offering a promising alternative to traditional diagnostic techniques.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords