Keywords: Peripheral Nerves, Diffusion Reconstruction, Guillain-Barre syndrome, MR neurography, tibial nerve, common peroneal nerves
Motivation: The accurate imaging evaluation of peripheral nerve injury in Guillain–Barre syndrome (GBS) patients is limited but crucial for clinical diagnosis and treatment.
Goal(s): To explore the value of MR neurography (MRN) in evaluating the peripheral nerve injury in GBS patients.
Approach: This prospective study involved lower limbs MRN scans of 36 GBS patients and healthy volunteers respectively. The correlation between cross-sectional areas (CSA) and signal-to-noise ratio (SNR) values, nerve scores and electrophysiology parameters of GBS group were compared.
Results: MR neurography showed larger CSA, higher SNR values in GBS patients (P<0.05). The SNR values and nerve scores were correlated with electrophysiological parameters (P<0.05).
Impact: This study suggested that MRN can evaluate different degrees of peripheral nerve injury in GBS patients and confirmed the correlation with electrophysiological parameters.
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