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Abstract #4178

Prognostic value of extracellular volume fraction in myocardial infarction and myocardial infarction with nonobstructive coronary arteries

Bowen Li1, Ximing Wang2, and Hui Gu2
1Shandong First Medical University, Jinan, China, 2Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China

Synopsis

Keywords: Atherosclerosis, Cardiovascular

Motivation: The prognosis of patients with myocardial infarction with nonobstructive coronary arteries (MINOCA) is not ideal, and prognostic stratification of ischemic MINOCA patients is still lacking.

Goal(s): The aim of this study was to evaluate the prognostic role of the extracellular volume fraction (ECV) in patients with MI and MINOCA.

Approach: From CMR imaging, the extent of late gadolinium enhancement (LGE), native T1 and ECV were derived. Follow-up was performed to assess major adverse cardiovascular events (MACEs).

Results: ECV was an independent predictor of MACEs. Similarly, ECV maintained an independent association with MACEs in the MINOCA and obstructive MI groups.

Impact: ECV demonstrated a strong prognostic association with MACEs and provided additional predictive value beyond common clinical and CMR risk factors. Furthermore, MINOCA is not a benign disease, their long-term prognosis is as poor as that of patients with obstructive MI.

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