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Abstract #4239

A fluid-sensitive MRI protocol for the small joints of the hand using a portable 46 mT scanner

Beatrice Lena1, Javad Parsa1, Simonetta R.G. van Griethuysen2, Dennis A. Ton2, Yiming Dong1, Annette H.M. van der Helm -van Mil2, and Andrew Webb1
1C.J. Gorter MRI Center, Radiology Department, Leids Universitair Medisch Centrum, Leiden, Netherlands, 2Department of Rheumatology, Leids Universitair Medisch Centrum, Leiden, Netherlands

Synopsis

Keywords: Low-Field MRI, Low-Field MRI, Fluid-sensitive protocol, small joints

Motivation: Early detection of subclinical joint inflammation, crucial for rheumatoid arthritis (RA) risk assessment, often requires costly, patient-unfriendly high-field MRI. Low-field, portable MRI offers an accessible alternative for primary care.

Goal(s): To develop a non-invasive fluid-sensitive MRI protocol to identify joint tissue inflammation using a portable 46-mT scanner.

Approach: We overlayed images acquired with T1-weighted scans, that clearly depict the main anatomical structures, with fat-suppressed T2-weighted scan, to achieve fluid contrast in the hand.

Results: Our protocol effectively visualizes anatomical details and fluid contrast, identifying signs of inflammation and incidental conditions in volunteers, showing promise for accessible, non-invasive RA screening in various healthcare settings.

Impact: In this study, we developed a fluid-sensitive MRI protocol for a portable 46 mT system. This method allows to capture both anatomical structures and fluid details, while ensuring comfortable scanning, showing potential for affordable, accessible joint inflammation detection.

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