Keywords: Myocardium, Myocardium, dynamic T1 mapping, contrast enhancement, free-breathing, whole-heart
Motivation: Early gadolinium enhancement has the potential for myocardial tissue characterization while not yet widely adopted due to the natural of the contrast agent kinetics.
Goal(s): This study aims to develop a Dynamic Approach for Rapid T1 mapping (DART) to quantify the dynamic T1 values with sufficient spatial-temporal resolution and whole heart coverage.
Approach: DART combined dynamic and stable phase into a single free-breathing scan with interleaved slice-tracking multi-slice acquisition. By sharing the equilibrium magnetization estimated from the stable phase, dynamic T1 was calculated.
Results: DART sequence was validated through phantom and in-vivo studies. The dynamic T1 time course can be traced successfully.
Impact: The porposed DART sequence is feasible to quantify the dynamic pixel-wised myocardial T1 values with sufficient spatial-temporal resolution and whole heart coverage. It is potential useful to trace the dynamic response of myocardium during early gadolinium enhancement.
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