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Abstract #4477

Design and development of a transmit RF coil for large field of view hyperpolarized 13C imaging

Albert P Chen1, Takashi Ishiguro2, Fraser Robb3, David Anderson3, Tony Thomas3, Jana Vincent3, Venkata Rao Malasani3, Victor Taracila3, Thomas Grafendorfer3, Edward Baus3, Thomas Stickle3, Atsushi Nozaki2, Justin Lau3, Arnaud Comment4, Charles H Cunningham5, and Kayvan R Keshari6,7
1GE Healthcare, Taichung, Taiwan, 2GE Healthcare, Hino, Japan, 3GE Healthcare, Aurora, OH, United States, 4GE Healthcare, Cambridge, United Kingdom, 5Physical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada, 6Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, 7Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, NY, United States

Synopsis

Keywords: Hyperpolarized MR (Non-Gas), Hyperpolarized MR (Non-Gas)

Motivation: To bring hyperpolarized 13C body imaging to its full potential.

Goal(s): Develop a 13C transmit coil that can provide large FOV coverage with uniform B1+ field, while minimizing impact to patient access and comfort.

Approach: An asymmetric 8 rung high-pass birdcage coil was designed to sit directly on the patient cradle. The prototype coil was constructed as a flat base along with a detachable top cage.

Results: The B1 maps acquired using the 13C birdcage coil in T/R mode showed good uniformity. The coil also performed as expected as a Tx only coil.

Impact: The 13C transmit coil developed in this project provides uniform RF excitation across a large FOV without compromising patient comfort and the 1H imaging. It will be an integral element for routine clinical HP 13C metabolic imaging in the future.

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