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Abstract #4482

Modular integration of spatial-spectral selective excitation into Bruker Singlepulse, Flash, and EPI for metabolite selective HP 13C MRSI

Christoph A. Müller1, Julian Schüle2, Swathi Hedge3, Alastair Marshall3, Jakob Gaubatz4, Luca Nagel4, Pascal Rütten1, Shai Machnes3, Franz Schilling4, Volker Rasche2, and Ilai Schwartz1
1NVision Imaging Technologies GmbH, Ulm, Germany, 2Internal Medicine II, Ulm University Medical Center, Ulm, Germany, 3Qruise GmbH, Saarbrücken, Germany, 4Technical University of Munich, School of Medicine and Health, Department of Nuclear Medicine, TUM University Hospital, Munich, Germany

Synopsis

Keywords: Hyperpolarized MR (Non-Gas), Hyperpolarized MR (Non-Gas), Spatial-Spectral RF Pulse

Motivation: Metabolite-selective MR imaging via spatial-spectral excitation has become an important method in hyperpolarized 13C MRI. Open-access optimization tools provide numerous RF & gradient solutions for a desired spatial-spectral band.

Goal(s): To provide solutions for users to test and verify the RF & gradient shape options via using standard MRI methods.

Approach: In this work, we implemented a modular feature in Bruker ParaVision that allows the selection of customized pulses & gradients in product methods.

Results: The feature was successfully implemented and tested in Singlepulse, FLASH, and EPI methods with minimal necessary reprogramming. Exemplary simulated and measured excitation profiles are presented.

Impact: A modular framework for spatial-spectral excitation with Bruker product methods was implemented. The framework can assist MRI researchers to evaluate possible RF & gradient shapes for a specified metabolite-selective MR exam.

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