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Abstract #4498

Efficacy of IVIM in differentiating invasive micropapillary carcinoma and fibroadenoma with rapid rising TIC curve

Yueqi Wu1, Lina Zhang1, Siqi Zhao1, Yuanfei Li1, Moyun Zhang1, Dandan Zheng2, and Liangjie Lin2
1The First Affiliated Hospital of Dalian Medical University, Dalian,China, China, 2Clinical & Technique Support, Philips Healthcare, Beijing, China

Synopsis

Keywords: fMRI Analysis, Diagnosis/Prediction, Breast cancer; invasive micropapillary carcinoma; fibroadenoma; Diffusion-weighted imaging; Intravoxel Incoherent Motion

Motivation: Differentiating invasive micropapillary carcinoma (IMPC) from fibroadenoma with rich enhancement can be challenging in preoperative MRI diagnosis.

Goal(s): Aim to verify whether Intravoxel Incoherent Motion (IVIM) imaging can enhance differential efficiency between IMPC and fibroadenoma, both exhibiting a rapid rise in Time-Intensity Curve (TIC).

Approach: The conventional MR features, and IVIM data of patients with pathologically proven tumors (12 IMPC and 8 fibroadenoma) were retrospectively analyzed.

Results: The D value derived from IVIM model provides quantitative information that aids in differentiating IMPC from fibroadenoma with a rapid-rising TIC. The apparent diffusion coefficient (ADC) value is also useful for distinguishing between the two diseases.

Impact: The ADC (b=1000 s/mm²) and D value derived from IVIM model are helpful to provide quantitative information for the differentiation of rapid-rising TIC IMPC from fibroadenoma.

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Keywords