Keywords: fMRI Analysis, Diagnosis/Prediction, Breast cancer; invasive micropapillary carcinoma; fibroadenoma; Diffusion-weighted imaging; Intravoxel Incoherent Motion
Motivation: Differentiating invasive micropapillary carcinoma (IMPC) from fibroadenoma with rich enhancement can be challenging in preoperative MRI diagnosis.
Goal(s): Aim to verify whether Intravoxel Incoherent Motion (IVIM) imaging can enhance differential efficiency between IMPC and fibroadenoma, both exhibiting a rapid rise in Time-Intensity Curve (TIC).
Approach: The conventional MR features, and IVIM data of patients with pathologically proven tumors (12 IMPC and 8 fibroadenoma) were retrospectively analyzed.
Results: The D value derived from IVIM model provides quantitative information that aids in differentiating IMPC from fibroadenoma with a rapid-rising TIC. The apparent diffusion coefficient (ADC) value is also useful for distinguishing between the two diseases.
Impact: The ADC (b=1000 s/mm²) and D value derived from IVIM model are helpful to provide quantitative information for the differentiation of rapid-rising TIC IMPC from fibroadenoma.
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