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Abstract #4583

The age-related trend in the diffusion tensor image analysis along the perivascular space (DTI-ALPS)

Xinyue Lyu1, Yi Yin1, Yongwen Sun1, Xiaoyan Lei1, Kai Ai2, and Bo Gao1
1Department of Radiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China, 2Department of Clinical and Technical Support, Philips Healthcare, Xi'an, China

Synopsis

Keywords: Aging, DWI/DTI/DKI, ALPS

Motivation: The Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) has been applied to the study of various diseases. However, the changes in their trajectories throughout the lifespan remain unclear.

Goal(s): To explore the trajectory of ALPS changes throughout adulthood.

Approach: Using linear, polynomial, and exponential models to characterize the life trajectory of ALPS.

Results: The polynomial model best represents the life trajectory of the left ALPS, while the linear model most effectively represents the right ALPS.

Impact: This study contributes to understanding the relationship between ALPS and age and the differences in ALPS between the two hemispheres of the brain.

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Keywords