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Abstract #4595

Motion-aware deep learning reconstruction for accelerated free-breathing ZTE lung MRI

Enlin Qian1, Victor Murray1, Anthony Mekhanik1, Jose de Arcos2, Florian Wiesinger3, and Ricardo Otazo1,4
1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States, 2GE Healthcare, Little Chalfont, United Kingdom, 3GE Healthcare, Munich, Germany, 4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States

Synopsis

Keywords: Machine Learning/Artificial Intelligence, Motion Correction, fast and free-breathing lung imaging

Motivation: Lung structural changes are important for respiratory disease diagnosis. ZTE imaging is suitable for ultra-short T2 or T2* MRI and has applications in lung imaging. Challenges in ZTE imaging include long scan time and respiratory motion.

Goal(s): To develop a DL-based motion-resolved reconstruction method for faster ZTE lung imaging.

Approach: Spiral phyllotaxis interleaves are sorted into four motion states using respiratory motions extracted from low-resolution ZTE images. A deep-learning network was trained to reconstruct images from accelerated acquisitions.

Results: The proposed ZTE-Movienet enables 1.72-fold acceleration with scan time of ~3.5 minutes with image quality comparable to a conventional ZTE acquisition of 6.5 minutes .

Impact: Deep learning motion-aware reconstruction of ZTE imaging enables accelerated motion-robust acquisition, which has the potential to promote the use of lung MRI in clinical practice.

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