Keywords: Novel Contrast Mechanisms, Neuroscience, Spin-Lock, Rotary Excitation, Deep Brain Stimulation
Motivation: A Rotary Excitation (REX) based detection method was developed for field calibration of neurostimulation. In future, this non-invasive imaging technique could enable to localize brain regions under multi-frequency interference stimulation and thus to analyze correlation between stimulated cortical and subcortical regions and outcome.
Goal(s): Investigate whether REX imaging enables frequency-specific field detection in the presence of multi-frequency magnetic fields.
Approach: As a proof-of-concept the MRI gradient system was used to project two magnetic fields (f1=100Hz, f2=200Hz) of locally varying magnitudes onto brain tissue of a healthy subject.
Results: Detection and discrimination of the magnetic fields was possible with a spatial resolution of 2x2x5mm.
Impact: So far, non-invasive methods for patient-specific imaging of evoking fields induced by deep-brain-stimulation (DBS) do not exist. REX-based imaging could enable structured assessment of stimulation target regions via MRI and thus support the calibration and clinical testing of neurostimulation devices.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords