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Abstract #4779

Fourier Informed Native Deblurring (FIND): A Robust Solution for Blurring in pseudo-Continuous Arterial Spin Labeling (pCASL) MRI

Mauro Zucchelli1, Ottavia Dipasquale1, Christos Papageorgakis1, Valentin H. Prevost2, Emilie Poirion3, Julien Savatovsky3, Bruno Triare2, and Stefano Casagranda1
1Department of R&D Advanced Applications, Olea Medical, La Ciotat, France, 2Canon Medical Systems Corporation, Tochigi, Japan, 3Imaging department, Hospital Foundation A. de Rothschild, Paris, France

Synopsis

Keywords: Arterial Spin Labelling, Arterial spin labelling, Deblurring

Motivation: The low resolution of pCASL MRI leads to blurring effects that hinder brain tissue differentiation and reduce diagnostic accuracy, highlighting the need for an effective deblurring solution.

Goal(s): Develop FIND (Fourier Informed Native Deblurring), a method to restore high-frequency image details missing in pCASL MRI acquisitions.

Approach: FIND uses a Fourier-based deblurring filter calculated from a reference image to correct blurring artifacts in pCASL MRI.

Results: FIND achieves significant improvements in image clarity, tissue contrast, and diagnostic precision in brain imaging.

Impact: FIND improves pCASL MRI image quality, enabling a more accurate assessment of brain pathologies and advancing clinical imaging applications.

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