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Abstract #4797

Cardiac Magnetic Resonance T1 Mapping Combined with Myocardial Diffusion Technique for Evaluating Fibrosis in Hypertensive Heart Disease (HHD)

Xiaowei Ruan1 and Xiuzheng Yue2
1Ningxia Hui Autonomous Region People's Hospital, Ningxia,yinchuan, China, 2Philips Healthcare, Beijing, China

Synopsis

Keywords: DWI/DTI/DKI, Cardiovascular

Motivation: This study evaluates the feasibility of combining CMR T1 mapping and Second MoCo cDWI to assess myocardial fibrosis in hypertensive heart disease (HHD) patients.

Goal(s): To provide a new non-invasive, quantitative, contrast-free method for the assessment of diffuse myocardial fibrosis.

Approach: Compared to healthy controls, HHD patients showed significantly higher T1 values and lower ADC values.

Results: The combined T1 and ADC values demonstrated high diagnostic efficacy for identifying myocardial fibrosis (AUC = 0.98), providing a new non-invasive and quantitative approach without using contrast agents.

Impact: This study provides a quantitative assessment of myocardial fibrosis in HHD patients using T1 mapping combined with MoCo cDWI, supporting fibrosis diagnosis.

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Keywords