Keywords: DWI/DTI/DKI, Cardiovascular
Motivation: This study evaluates the feasibility of combining CMR T1 mapping and Second MoCo cDWI to assess myocardial fibrosis in hypertensive heart disease (HHD) patients.
Goal(s): To provide a new non-invasive, quantitative, contrast-free method for the assessment of diffuse myocardial fibrosis.
Approach: Compared to healthy controls, HHD patients showed significantly higher T1 values and lower ADC values.
Results: The combined T1 and ADC values demonstrated high diagnostic efficacy for identifying myocardial fibrosis (AUC = 0.98), providing a new non-invasive and quantitative approach without using contrast agents.
Impact: This study provides a quantitative assessment of myocardial fibrosis in HHD patients using T1 mapping combined with MoCo cDWI, supporting fibrosis diagnosis.
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