Meeting Banner
Abstract #4863

Neural correlates differ between crystallized and fluid intelligence in adolescents: A Multi-modal MRI Investigation

Bowen Qiu1, Rui Qian1, Baorong Gu1, Zichao Li1, Zhifan Chen1, Xinyi Xu1, Yiwei Chen1, Ruoke Zhao1, Ruike Chen1, Yuqi Zhang1, Zhiyong Zhao1,2, Mingyang Li1, and Dan Wu1
1Key Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China, 2Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, hangzhou, China

Synopsis

Keywords: Neurotransmission, Adolescents

Motivation: Fluid and crystallized intelligence reflect distinct cognition abilities in adolescents, but their specific neurobiological basis and environmental influences remain unclear. Multi-modal MRI offers valuable insights into the neural features associated to each intelligence form.

Goal(s): This study aimed to distinguish MRI-phenotype basis for fluid/crystallized intelligence in adolescents, and identify neural basis and lifestyle impact.

Approach: We analyzed multi-modal MRI data and intelligence measurement from ABCD study, integrating with brain gene expression and neurotransmitter density.

Results: Fluid intelligence was associated with dMRI phenotypes while crystallized intelligence was associated with sMRI phenotypes. Both forms of intelligence have distinct neural, molecular basis and lifestyle impact.

Impact: From the perspective of multi-modal MRI, this study provided valuable insights into the distinct neural and molecular basis of adolescent intelligence, paving the way for educational strategies and potential interventions. It also offered basis for future research into cognitive development.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords