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Abstract #4888

High resolution sub-voxel magnetic susceptibility source separation of pigeon head at 14.1T

Hongyi Yang1, Lulu Wang1, Zishuo Li2, Juan Li2, Minghong Wang2, Changlin Tian2, and Qiong Ye1
1High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China, 2University of Science and Technology of China, Hefei, China

Synopsis

Keywords: Head & Neck/ENT, Susceptibility

Motivation: The precise mechanisms through which pigeons detect and utilize the Earth’s magnetic field for orientation and navigation remain to be fully explored. The χ-separation, which is capable of disentangling the sub-voxel contributions of paramagnetic and diamagnetic susceptibility, is utilized to provide novel insights into this physiological processes.

Goal(s): To investigate the distribution of paramagnetic and diamagnetic susceptibility in the pigeon head using the χ-separation technique.

Approach: Ex vivo pigeon head was scanned at 14.1T MRI with 100 µm isotropic resolution.

Results: The results demonstrate that the χ-separation technique can provide previously unseen information on the distribution of paramagnetic and diamagnetic susceptibility.

Impact: The distribution of paramagnetic and diamagnetic susceptibility disentangled by χ-separation could provide new insights into the understanding of the mechanisms by which pigeons sense and use the Earth’s magnetic field for orientation and navigation.

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