Keywords: Parkinson's Disease, fMRI (resting state)
Motivation: Resting-state functional magnetic resonance imaging (rs-fMRI) and ¹H magnetic resonance spectroscopy (MRS) offer complementary insights into brain function and metabolism.
Goal(s): To investigate the relationship between changes in brain function and metabolism in patients with Parkinson’s disease (PD) using rs-fMRI and MRS techniques.
Approach: The anterior cingulate cortex (ACC) was selected as the region of interest, and correlations between alterations in brain function and metabolic markers, such as γ-aminobutyric acid and macromolecules (GABA+), were evaluated.
Results: A significant negative correlation was observed between ALFF values and GABA+ levels in the ACC.
Impact: Integrating rs-fMRI and MRS in PD research could uncover the bidirectional relationship between functional connectivity and metabolism, enhancing our understanding of future brain dynamics changes.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords