Keywords: Preclinical Image Analysis, Animals
Motivation: Many brain chemicals are of critical importance in alcohol-related neuropathology and in fact are targeted by different measurement methodologies: molecular imaging methods such as PET and SPECT to study various receptors present in the brain. To create a measurable signal, however, it is necessary to inject specifically synthesized short-lived radioactive tracers into the blood stream
Goal(s): Magnetic resonance spectroscopy (MRS) on the other hand does not require the use of an exogenous agent to yield a signal from chemicals in the brain.
Approach: In vivo 1H MRS performed in a selected ROI
Results: Myo-Ins depletion could be astrocytes response against cell swelling.
Impact: In vivo 1H magnetic resonance spectroscopy techniques were applied to reveal biochemical changes in the mouse brain caused by prolonged ethanol consumption.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords