Keywords: Other Musculoskeletal, PET/MR, Diagnosis/Prediction, Inflammation, Molecular Imaging, MSK
Motivation: There is a critical unmet need for accurate detection of pain generating foci to enable treatment of patients suffering from chronic pain.
Goal(s): To evaluate the clinical impact of FDG PET/MRI in patients among whom conventional diagnostic imaging and therapies had not achieved pain remission.
Approach: A single-center retrospective study of patients who underwent PET/MRI with clinical follow up to determine if PET/MRI altered management, and if so, whether pain reduction was achieved.
Results: PET/MRI resulted in change in management for 30/41 patients. Among those where post-PET/MRI pain score was available, there was a significant reduction in pain score by 34%.
Impact: FDG PET/MRI is a promising tool in management of patients with chronic pain among whom the origin of pain remains unknown. Further validation through larger multi-center studies with appropriate controls are needed before widespread implementation.
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