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Abstract #4961

Clinical Utility of FDG PET/MRI in Detection of Pain Generators in Patients with Chronic Pain

Fatemeh Rashidi1, Raphael do Vale Souza 1, Sandip Biswal1, and Ali Pirasteh1,2
1Department of Radiology, University of Wisconsin–Madison, Madison, WI, United States, 2Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States

Synopsis

Keywords: Other Musculoskeletal, PET/MR, Diagnosis/Prediction, Inflammation, Molecular Imaging, MSK

Motivation: There is a critical unmet need for accurate detection of pain generating foci to enable treatment of patients suffering from chronic pain.

Goal(s): To evaluate the clinical impact of FDG PET/MRI in patients among whom conventional diagnostic imaging and therapies had not achieved pain remission.

Approach: A single-center retrospective study of patients who underwent PET/MRI with clinical follow up to determine if PET/MRI altered management, and if so, whether pain reduction was achieved.

Results: PET/MRI resulted in change in management for 30/41 patients. Among those where post-PET/MRI pain score was available, there was a significant reduction in pain score by 34%.

Impact: FDG PET/MRI is a promising tool in management of patients with chronic pain among whom the origin of pain remains unknown. Further validation through larger multi-center studies with appropriate controls are needed before widespread implementation.

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Keywords