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Abstract #5050

Preliminary Findings from a Longitudinal Study on Intracranial Atherosclerotic Disease and Stroke Risk in Brain Tumor Patients

Beibei Sun1, Mohamed HD Hassan1, Mohamad H Mosi1, Ahmed A Safwat1, Chengcheng Zhu1, and Mahmud Mossa-basha1
1University of Washington, SEATTLE, WA, United States

Synopsis

Keywords: Atherosclerosis, Atherosclerosis, brain tumor

Motivation: As cancer survival rates have improved in recent years, it is crucial to identify survivors at elevated stroke risk.

Goal(s): To assess ICAD and track acute ischemic stroke (AIS) incidence in brain tumor patients, offering valuable insights into the vascular health of this high-risk group.

Approach: Developing a unique longitudinal vessel wall MRI (IVW) database to assess ICAD and track acute ischemic stroke (AIS) incidence in brain tumor patients.

Results: Significant prevalence of intracranial atherosclerotic plaques among brain tumor patients, with an increase in plaque burden over time. The incidence of acute ischemic stroke in brain tumor patients is 4.9%.

Impact: The incidence of AIS in brain tumor patients, albeit low, underscores the need for vigilant cardiovascular monitoring in this high-risk group.These findings highlight the importance of early detection and management of ICAD to mitigate stroke risk and improve patient outcomes.

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