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Abstract #5165

Value of dynamic contrast-enhanced MRI in the diagnosis of acute radiation-induced rectal injury: a comparison with endoscopy

Wen-jie FAN1, Zi-qiang WEN2, Quan-meng LIU2, Yu-ru MA2, Yi-yan LIU2, Bao-lan LU2, Jian-peng YUAN3, Shen-ping YU2, and Yan CHEN2
1The First Affiliated Hospital, Sun Yat-sen University; The Seventh Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, 2The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, 3The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China

Synopsis

Keywords: Digestive, Perfusion

Motivation: The postoperative anastomotic fistula of rectal cancer is affected by radiation proctitis. Radiation proctitis is mainly evaluated by endoscopy, which is invasive and subjective.

Goal(s): To investigate the value of DCE-MRI parameters in diagnosising acute radiation-induced rectal injury.

Approach: In a retrospective analysis, DCE-MRI parameters of rectal wall in 49 patients after neoadjuvant chemoradiotherapy were measured and compared with the evaluation of Vienna endoscopy.

Results: Ktrans in patients with acute RRI was significantly lower compared to those without acute RRI, with a AUC of 0.80.

Impact: DCE-MRI is an appropriate non-invasive imaging technique for diagnosing acute RRI in patients with rectal cancer.

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Keywords