Abstract #5282

Accelerated 4D Flow with Respiratory Compensation and Cardiac View Sharing in Pediatric Congenital Heart Disease

Fatemeh Rastegar Jooybari^1,2, Christopher Huynh², Sharon Portnoy², Jonathan Voutsas³, Diana Balmer-Minnes², Ankavipar Saprungruang⁴, Shi-Joon Yoo⁵, Christopher Z Lam⁴, and Christopher K Macgowan^1,2

¹Medical Biophysics, University of Toronto, Toronto, ON, Canada, ²Translational Medicine, Hospital for Sick Children, Toronto, ON, Canada, ³Queen's University, Kingston, ON, Canada, ⁴Diagnostic Imaging, Hospital for Sick Children, Toronto, ON, Canada, ⁵Medical Imaging and Paediatrics, University of Toronto, Toronto, ON, Canada

Synopsis

Keywords: Cardiovascular, Flow, compressed sensing, cardiovascular MRI, 4D flow, pediatrics, congenital heart disease

Motivation: Long scan times in conventional 4D flow MRI limit its use in pediatric congenital heart disease (CHD) due to motion artifacts and patient discomfort.

Goal(s): To evaluate an accelerated 4D flow MRI technique that reduces scan time while maintaining flow quantification accuracy in pediatric CHD patients.

Approach: We demonstrate a 5-minute free-breathing 4D flow MRI protocol using compressed sensing, respiratory soft-gating, and cardiac view-sharing. Flow estimates were compared with conventional 2D phase contrast MRI.

Results: The accelerated method provided accurate flow quantification, with strong agreement to 2D PCMR and reduced scan time compared to conventional 4D flow.

Impact: This study shows that accelerated 4D flow MRI can shorten scan times while maintaining accuracy, improving clinical workflow and patient comfort in pediatric congenital heart disease.

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