Abstract #5316

Histogram analysis of quantitative parameters for prostate cancer and prostatic hyperplasia: A Preliminary 5.0 T MRI Study

chengfeng zheng^1,2, sen xing², xinghua liu³, wenbing zeng³, shaoxin xiang⁴, huan ma³, zhichao feng⁵, and ying xiong³

¹Department of Radiology, Graduate School of Jinzhou Medical University, ,Jinzhou City, China, ²Department of Radiology, Three Gorges Hospital, Chongqing University, Chongqing, China, ³Department of Radiology, Three Gorges Hospital, Chongqing University, chongqing, China, ⁴Beijing Union Image Intelligent Imaging Technology Research Institute, beijing, China, ⁵Union Image Central Research Institute, shanghai, China

Synopsis

Keywords:

Motivation: Multiparametric MRI on 5T has emerged as a pivotal diagnostic modality for evaluating body lesions, but its application in prostate imaging has not been fully explored.

Goal(s): To evaluate the diagnostic efficacy of distinguishing PCa from BPH using multiparametric histogram analysis on 5.0T MRI

Approach: 85 patients underwent DWI, IVIM, and T2 mapping imaging on 5.0T MRI, and diagnostic performance of combined ADC_D_D*_f_T2 model was assessed.

Results: The combined ADC_D_D*_f_T2 model achieved an AUC of 0.991 on 5T, significantly outperforming PSA testing in distinguishing PCa from BPH.

Impact: This study demonstrates that 5.0T MRI, with advanced histogram analysis, offers a reliable and non-invasive method for distinguishing prostate cancer from benign prostatic hyperplasia, enabling more accurate early diagnoses and reducing unnecessary biopsies in clinical settings.

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