Meeting Banner
Abstract #5357

Effect of Impaired Glymphatic system on the Short-term Prognosis of Patients with Acute Ischemic Stroke: A Clinical Study Based on MRI Indices

Xiaolan Du1 and Xirui Duan1
1Radiology department, Yan 'an Hospital Affiliated to Kunming Medical University, Kunming, China, China

Synopsis

Motivation: Research has shown that the glymphatic system is impaired in stroke patients, but its pattern of changes remains unclear.

Goal(s): Combine the DTI-ALPS index and perivascular space volume to explore the short-term changes in the glymphatic system after acute ischemic stroke and their impact on neurological function.

Approach: The NIHSS score was used to assess neurological deficits in AIS patients at 24 hours, 7 days, and 3 months after treatment. MRI was used to quantify the DTI-ALPS index and PVS volume.

Results: A higher ALPS index and early recovery of local PVS volume were closely associated with improved neurological function.

Impact: Exploring the dynamic changes in the brain's glymphatic system after stroke helps deepen the understanding of stroke mechanisms and contributes to research aimed at improving recovery in ischemic stroke patients.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords